Packaging and distribution is essential to the success of open-source Python projects. This tutorial covers the process of turning a simple Python script into a package that can be uploaded to the Python Package Index. In addition to basic and advanced use of distutils and Setuptools, it explores integration of documentation, unit testing, code quality assurance, continuous integration, and Python 2/3 compatibility. By the end of the tutorial, participants will have a full Python package which can be used as a basis for future Python projects.